1. On April 22, 1871, the first issue of the St. Joseph Daily Gazette was published in St. Joseph, Missouri. This newspaper would go on to become one of the longest-running papers in the state and was known for its coverage of important events and issues.

2. On April 22, 1904, the Louisiana Purchase Exposition (also known as the St. Louis World's Fair) opened in St. Louis, Missouri. This event attracted nearly 20 million visitors and showcased the latest technological and cultural advancements of the time.

3. On April 22, 1928, the Missouri State Highway Patrol was established by the state legislature. This law enforcement agency is responsible for ensuring public safety on Missouri's highways and has grown to include over 1,200 troopers and hundreds of civilian employees.

4. On April 22, 1941, the Jefferson City Airport was dedicated in Jefferson City, Missouri. This airport served as an important hub for air transportation in the central part of the state and helped to connect Missouri to the wider world.

5. On April 22, 1994, the Kansas City Royals played their first game at their new stadium, Kauffman Stadium. This state-of-the-art stadium has hosted many important events over the years and is considered one of the best baseball parks in the country.