1. In 1943, South Dakota’s largest and deadliest tornado occurred on May 6, resulting in 11 fatalities and over 100 injuries.

2. On May 6, 1877, Crazy Horse, a prominent Lakota warrior and leader, surrendered to U.S. authorities at Fort Robinson, Nebraska, effectively ending the Sioux Wars.

3. May 6, 1888 marked the official opening of the Homestake Mine in Lead, South Dakota. The mine would become one of the largest and deepest gold mines in North America, operating for over 125 years before closing in 2002.

4. In 1933, President Franklin D. Roosevelt signed the National Industrial Recovery Act, which established the Civilian Conservation Corps (CCC). The CCC provided jobs for young men and conservation work, including in South Dakota's Black Hills.

5. On May 6, 1960, the first nuclear bomb was detonated at the Nevada Test Site as part of the U.S. nuclear testing program. While the tests did not occur in South Dakota, their impact was felt across the nation, including in the nearby Pine Ridge Indian Reservation, which was exposed to high levels of radiation.