1. On November 16, 1817, Maryland's first railway was chartered, the Baltimore and Ohio Railroad Company, which went on to become a major rail service provider in the eastern United States.

2. In 1907, the first game was played at the newly constructed Johns Hopkins University Homewood Field, which would go on to host many notable sporting events and concerts over the years.

3. On November 16, 1933, the historic B&O Railroad Station in Cumberland, Maryland was destroyed by fire. The station had been a major transportation hub for the region, and its loss was felt deeply by the local community.

4. In 1950, the United States Naval Academy's football team defeated the University of Maryland 35-21 at Municipal Stadium in Baltimore, in what is considered one of the greatest upsets in college football history.

5. On November 16, 2012, Baltimore-based television station WMAR-TV made history by becoming the first broadcast television station in the United States to transmit its program signal using the new ATSC 2.0 broadcasting standard.