1. On October 25, 1764, the Province of Massachusetts Bay passed the Sugar Act, a law imposed by the British Parliament to raise revenue from the American colonies by taxing sugar, molasses, and other commodities. The act led to widespread protests and was one of the precursors of the American Revolution.

2. On October 25, 1854, Massachusetts senator Charles Sumner delivered a speech denouncing slavery and the Kansas-Nebraska Act, which sought to allow slavery in new territories. As a result, Sumner was assaulted on the Senate floor by South Carolina representative Preston Brooks, who beat him unconscious with a cane.

3. On October 25, 1906, the first electric streetcars ran in Boston, replacing the older horse-drawn carts. This marked a major milestone in the city's transportation history and helped to modernize Boston's urban infrastructure.

4. On October 25, 1960, John F. Kennedy gave a speech at Symphony Hall in Boston to announce his candidacy for President of the United States. The event signaled the beginning of one of the most famous political campaigns in American history.

5. On October 25, 2018, a massive gas explosion rocked the Merrimack Valley region of Massachusetts, causing widespread damage and killing one person. The explosion was caused by over-pressurization of gas lines operated by Columbia Gas of Massachusetts, and led to a major controversy over the safety of natural gas infrastructure.