1. On September 22, 1826, James Whitcomb Riley, famous poet and writer, was born in Greenfield, Indiana. He is known for his poems that celebrate rural life and the common people.

2. The first electric streetcar in Fort Wayne, Indiana, began operating on September 22, 1887. The streetcar system provided convenient transportation for citizens and helped to spur economic growth in the city.

3. On September 22, 1903, the first automobile race in Indiana was held at the Indianapolis Fairgrounds. The race was won by Barney Oldfield, a famous race car driver of the time.

4. The Indiana State Fair, which is one of the largest and oldest state fairs in the United States, opened on September 22, 1852. The fair is a celebration of Indiana's agricultural heritage and features livestock shows, a midway, and agricultural exhibits.

5. September 22, 2000, saw the first game at the new Conseco Fieldhouse in Indianapolis. The arena serves as the home of the Indiana Pacers basketball team and hosts various concerts and entertainment events throughout the year.