1. On September 27, 1850, South Carolina Senator John C. Calhoun delivered his final speech in the United States Senate, arguing for Southern states' rights over the federal government. Calhoun, a proponent of slavery and a major figure in American politics, died the following year.

2. The Confederate States of America, which included South Carolina, signed a treaty of alliance with France on September 27, 1862. The treaty aimed to secure military support and recognition of the Confederacy as a sovereign nation, but it ultimately failed as France did not officially recognize the Confederate government.

3. One of South Carolina's most famous poets, Paul Hamilton Hayne, was born on September 27, 1830. Hayne wrote extensively about the South and its landscape, as well as his experiences during the Civil War.

4. South Carolina's first African American congressman, Robert Smalls, was born into slavery on September 27, 1839. Smalls famously stole a Confederate ship and surrendered it to Union forces during the Civil War, and later served in the U.S. House of Representatives during Reconstruction.

5. On September 27, 2016, South Carolina Governor Nikki Haley declared a state of emergency ahead of Hurricane Matthew, a major storm that caused flooding and significant damage in several coastal communities. The storm ultimately caused 46 deaths in the U.S. and prompted widespread evacuations and power outages.